The Prism Sound Lyra 1 and 2 are USB 2.0 interfaces with either 1 microphone + 1 instrument or 2 microphone and 2 instrument input plus digital S/PDIF I/O. The interfaces are available from November 2012. Likely to be in the higher price range.
The manufacturer claims the interfaces work on Linux due to UAC2 (USB Audio Class) compliance, but without support for the control panel software.